CREB-1(Phospho Thr100) Polyclonal Antibody, 50ul Mammalian Expression Hepatocyte nuclear factor 1-beta binds

Hepatocyte nuclear factor 1-beta binds to DNA as either a homodimer

Defects in the cathepsin C have been shown to be a cause of Papillon-Lefevre syndrome

In fact| in addition to providing a physical barrier| C-terminal fragments of this protein display antimicrobial activity against P

The precursor protein is cleaved into two chains that form a heterodimer linked by a disulfide bond

Defects in this gene are the cause of selective C1s deficiency

CREB-1(Phospho Thr100) Polyclonal Antibody, 50ul Mammalian Expression Hepatocyte nuclear factor 1-beta bindsThis gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms.