ITX3 il tartrate cis-22a is a TRPV6 inhibitor

cis-22a is a TRPV6 inhibitor (IC50 = 0

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as exhibited by their expression of mature RPE genes and phagocytosis of photoreceptor outer segments

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InChiKey: YYLKKYCXAOBSRM-JXMROGBWSA-N

ITX3 il tartrate cis-22a is a TRPV6 inhibitorITX3 is a nontoxic selective cell active inhibitor of the Trio RhoG Rac1 pathway. It acts by validating RhoGEFs as druggable targets. Product information CAS Number: 347323 96 0 Molecular Weight: 371. 45 Formula: C22H17N3OS Synonym: ITX 3 ITX 3 Chemical Name: (4E) 4 [(2,5 dimethyl 1 phenyl 1H pyrrol 3 yl)methylidene] 5 thia 2,7 diazatricyclo[6. 4. 0. 0,]dodeca 1(12),6,8,10 tetraen 3 one Smiles: CC1=C( C=C2 SC3=NC4=CC=CC=C4N3C 2=O)C=C(C)N1C1C=CC=CC=1