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Romidepsin Catalog No.:M8157-10 2019 May 2

SKU: 98226877813

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Romidepsin Catalog No.:M8157-10 2019 May 2Romidepsin, also known as FK228; is a bicyclic depsipeptide antibiotic isolated from the bacterium Chromobacterium violaceum with antineoplastic activity. After intracellular activation, romidepsin binds to and inhibits histone deacetylase (HDAC), resulting in alterations in gene expression and the induction of cell differentiation, cell cycle arrest, and apoptosis. This agent also inhibits hypoxia induced angiogenesis and depletes several heat shock

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Description

2019 May 2

Molecular Weight: 378

HCQ treatment has been shown to cause increased apoptosis

[Pharmacokinetics and disposition of triptonide in rats]

Free Radic Res

Romidepsin Catalog No.:M8157-10 2019 May 2Romidepsin, also known as FK228; is a bicyclic depsipeptide antibiotic isolated from the bacterium Chromobacterium violaceum with antineoplastic activity. After intracellular activation, romidepsin binds to and inhibits histone deacetylase (HDAC), resulting in alterations in gene expression and the induction of cell differentiation, cell cycle arrest, and apoptosis. This agent also inhibits hypoxia induced angiogenesis and depletes several heat shock

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