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KPT-330 - CAS# 1393477-72-9 Catalog No.:M6605-10 and improves glycaemic control

KPT-330 - CAS# 1393477-72-9 Catalog No.:M6605-10 and improves glycaemic control

Name: KPT-330 - CAS# 1393477-72-9 Catalog No.:M6605-10 and improves glycaemic control
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SKU: 95865965800
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SKU: 95865965800

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KPT-330 - CAS# 1393477-72-9 Catalog No.:M6605-10 and improves glycaemic controlKPT 330, CAS No. 1393477 72 9, is an orally bioavailable, potent and selective XPO1 CRM1 Inhibitor. KPT 330 is effective in acquired resistance to ibrutinib and synergizes with ibrutinib in chronic lymphocytic leukemia. KPT 330 potentiates the antitumor activity of gemcitabine in human pancreatic cancer through inhibition of tumor growth, depletion of the antiapoptotic proteins, and induction of apoptosis. KPT 330 has strong activity against primary

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and improves glycaemic control

3 μM and 1

Epub 2011 Jun 13

PFI-1 induces dose-dependent reduction of cell viability in T4302 CD133+ cells

and the extensive internalization was observed at 200 μm 6-OAU stimulation

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