CCT129202 - CAS# 942947-93-5 10575 Icosapent is a synthetic derivative
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CCT129202 - CAS# 942947-93-5 10575 Icosapent is a synthetic derivativeCCT129202 is an inhibitor of Aurora kinase activity and displays a favorable antineoplastic effect in preclinical studies. CCT129202 significantly reversed ABCB1 and ABCG2 mediated MDR in vitro, in vivo and ex vivo by inhibiting the function of their transporters and enhanced the eradication of cancer stem like cells by chemotherapeutic agents. CCT129202 may be a candidate as MDR reversal agent for antineoplastic combination therapy and merits further
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