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Y-39983 HCl - CAS# 173897-44-4 0217 InChi: InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8

Y-39983 HCl - CAS# 173897-44-4 0217 InChi: InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8

Name: Y-39983 HCl - CAS# 173897-44-4 0217 InChi: InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8
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Y-39983 HCl - CAS# 173897-44-4 0217 InChi: InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8Y 39983 HCl, CAS No. 173897 44 4, also known as Y 33075, is a potent and selective inhibitor of ROCK family with IC50 value of 3. 6nM for ROCK. Y 39983 attenuates experimental autoimmune encephalomyelitis via inhibition of demyelination. Y 39983 downregulates RhoA Rho associated kinase expression during its promotion of axonal regeneration. Y 39983, promotes regeneration of crushed axons of retinal ganglion cells into the optic nerve of adult cats.

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InChi: InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8

108(7):1318-1327

Marsilje TH

and by allergen (dust mite) in basophils (histamine release

Molecular Weight: 224

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