RO495 brary of Histone Demethylase 4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)isonicotinamide

4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)isonicotinamide

is a potent and specific aryl hydrocarbon receptor (AhR) antagonist

InChiKey: HIJMSZGHKQPPJS-UHFFFAOYSA-N

is an acyl coenzyme A: cholesterol acyltransferase (ACAT) inhibitor

Discovery of inhibitors that elucidate the role of UCH-L1 activity in the H1299 lung cancer cell line

RO495 brary of Histone Demethylase 4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)isonicotinamideRO495 (CS 2667) is a potent inhibitor of Non receptor tyrosine protein kinase 2 (TYK2). Product information CAS Number: 1258296 60 4 Molecular Weight: 389. 24 Formula: C17H14Cl2N6O Chemical Name: N [2 [(2 amino 6 methylpyrimidin 4 yl)amino]pyridin 4 yl] 2,6 dichlorobenzamide Smiles: CC1=CC(NC2=CC(=CC=N2)NC(=O)C2C(Cl)=CC=CC=2Cl)=NC(N)=N1 InChiKey: LNGDQKGREFSTHB UHFFFAOYSA N InChi: InChI=1S C17H14Cl2N6O c1 9 7 14(25 17(20)22 9)24 13 8 10(5 6 21 13)23