Bazedoxifene acetate Catalog No.:M10044-2 2-diphenylacetate hydrochloride

2-diphenylacetate hydrochloride

Oral administration of CX-4945 at 25 mg/kg or 75 mg/kg twice daily displays potent antitumor activity in the BT-474 model

2R)-2-hydroxycyclohexyl]amino}-1

1H2/b22-16+

TCS-JNK-6a binds competitively and reversibly to the ATP site

Bazedoxifene acetate Catalog No.:M10044-2 2-diphenylacetate hydrochlorideBazedoxifene, also known as WAY 140424, is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals. In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis. Bazedoxifene is an indole based ER ligand that binds to both ER (IC50 = 26 nM) and ER (IC50 = 99