Dabrafenib - CAS# 1195765-45-7 size:10mg solid It possesses tumor-specific effect

It possesses tumor-specific effect

Precision Oncology for Hepatocellular Cancer: Slivering the Liver by FGF19-FGF4-KLB Pathway Inhibition

13(1):e0191010

Blachly JS

R112 does not inhibit the phosphorylation of Syk (Y352)

Dabrafenib - CAS# 1195765-45-7 size:10mg solid It possesses tumor-specific effectDabrafenib, CAS No. 1195765 45 7, also known as GSK2118436 , is an orally bioavailable inhibitor of B raf (BRAF) protein with potential antineoplastic activity. Dabrafenib selectively binds to and inhibits the activity of B raf, which may inhibit the proliferation of tumor cells which contain a mutated BRAF gene. B raf belongs to the the raf mil family of serine threonine protein kinases and plays a role in regulating the MAP kinase ERKs signaling