AG14361 ustat Rolipram forms a potent discriminative

Rolipram forms a potent discriminative stimulus in drug discrimination experiments in rats

[Lyell's syndrome]

Smiles: CC1=CC=CC=C1N1C(=O)C2=C(C=CC=C2C)N=C1CN1N=C(C2=C(N)N=CN=C12)C1=CC(O)=CC=C1

PubMed PMID: 21079728

36(9):1348-1357

AG14361 ustat Rolipram forms a potent discriminativeAG14361 is a PARP 1 inhibitor with Ki < 5 nmol L. AG14361 is at least 1000 fold more potent than the benzamides. The IC50 for AG14361 is 29 nM in permeabilized SW620 cells and 14 nM in intact SW620 cells. Product information CAS Number: 328543 09 5 Molecular Weight: 320. 39 Formula: C19H20N4O Synonym: AG 14361 Chemical Name: 1 (4 ((dimethylamino)methyl)phenyl) 8, 9 dihydro 2, 7, 9a triazabenzo[cd]azulen 6(7H) one. Smiles: