Crizotinib Hydrochloride - CAS# 1415560-69-8 Catalog No.:M10974-2 HSP90 or the 53 kinases

HSP90 or the 53 kinases tested

Formula: C25H28N6O2

by activating a certain family of voltage-gated potassium channels in the brain

In a concentration of 128 mcg/mL Triazavirin is shown active in inhibition of the tick-borne encephalitis virus reproduction (strain Sofiin) by accumulation in the SKEV cell culture

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Crizotinib Hydrochloride - CAS# 1415560-69-8 Catalog No.:M10974-2 HSP90 or the 53 kinasesCrizotinib (PF 02341066) hydrochloride (Xalkori) inhibits tyrosine phosphorylation of c Met and nucleophosmin (NPM) anaplastic lymphoma kinase (ALK) with IC50 of of 11 nM and 24 nM in cell based assays, respectively. Crizotinib hydrochloride is also a potent ROS1 inhibitor with Ki less than 0. 025 nM. Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines. Product information CAS Number: 1415560 69 8