GTPL5846 - CAS# 83797-69-7 273 (2015) PLoS One

(2015) PLoS One

Right now MK-1775 is in phase I/II clinical trials for various cancers

It is used in a chemical cocktail of seven small molecules to directly convert human fibroblasts into neuronal cells bypassing a neural progenitor stage

6-dichloro-1H-indole-3-propanoic acid

CAS Number: 55368-40-6

GTPL5846 - CAS# 83797-69-7 273 (2015) PLoS One6 OAU(GTPL5846; 6 n octylaminouracil), CAS No. 83797 69 7, is a surrogate agonist of GPR84; activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an EC50 of 105 nM in the PI assay. IC50 value: 105 nM Target: GPR84 agonist Product information CAS Number: 83797 69 7 Molecular Weight: 239. 31 Formula: C12H21N3O2 Chemical Name: 6 (Octylamino) 2,4(1H,3H) pyrimidinedione Smiles: CCCCCCCCNC1=CC(=O)NC(=O)N1 InChiKey: PFSWASUQURIOOR