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I-BET762 (GSK525762) - BET Inhibitor. CAS# 1260907-17-2 60186 Regulation of circadian behavior and

I-BET762 (GSK525762) - BET Inhibitor. CAS# 1260907-17-2 60186 Regulation of circadian behavior and

Name: I-BET762 (GSK525762) - BET Inhibitor. CAS# 1260907-17-2 60186 Regulation of circadian behavior and
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SKU: 58367518632
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SKU: 58367518632

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I-BET762 (GSK525762) - BET Inhibitor. CAS# 1260907-17-2 60186 Regulation of circadian behavior andI BET762 (GSK525762), CAS No. 1260907 17 2, is a novel, highly potent, selective and cell permeable inhibitor of the bromodomain and extra terminal (BET) family protein BRD4 with an IC50 of ~35 nM. It suppresses the production of proinflammatory proteins by macrophages and blocks acute inflammation. It is highly selective over other bromodomain containing proteins. In vivo studies using I BET762 have demonstrated efficacy in a range of oncology and

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Description

Regulation of circadian behavior and metabolism by synthetic REV-ERB agonists

11(2):242-52

Pehamberger H

Cyclopamine

Formula: C22H24Cl2N2O4

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