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doi: 10.1002/cbf.1618

Food Chemistry: X, 15 , 100398

Virus-induced down-regulation of G6PD occurred both at the transcriptional level via NRF2 modulation, and at the level of SIRT2-dependent deacetylation

Here the clinical investigations are contradictory

LRRK2 mutations (such as G2019S) promote mitochondrial fission in microglia by enhancing kinase activity, releasing mtROS and other factors to activate the NLRP3 inflammasome, exacerbating neuroinflammation in PD, and their regulation of mitochondrial dynamics has potential associations with ferroptosis (124)