Bicyclol Size:Solid 10 mg The pharmacology of TUG-891

The pharmacology of TUG-891

CAS Number: 439081-18-2

Chemical Name: (S)-4-(4-((4-chlorophenyl)(pyridin-2-yl)methoxy)piperidin-1-yl)butanoic acid compound with benzenesulfonic acid (1:1)

such as hydrogen peroxide

the IC50 for inhibition of RS4

Bicyclol Size:Solid 10 mg The pharmacology of TUG-891Bicyclol, also known as SY 801, is a hepatoprotective agent. Bicyclol upregulates transcription factor Nrf2, HO 1 expression and protects rat brains against focal ischemia. Bicyclol induces cell cycle arrest and autophagy in HepG2 human hepatocellular carcinoma cells through the PI3K AKT and Ras Raf MEK ERK pathways. Bicyclol attenuates tetracycline induced fatty liver associated with inhibition of hepatic ER stress and apoptosis in mice. Bicyclol