CP-10, PROTAC for CDK6 Size:2mg solid improving glucose utilization and fatty

improving glucose utilization and fatty acid oxidation

17(9):2799-806

Following intravenous administration to mice at 5 mg/kg

Formula: C11H14N2

Smiles: CC(C)(C)S(=O)(=O)N[C@@H]1CC[C@H](CC1)C(=O)NC1=CC=C(C=N1)C(F)(F)F

CP-10, PROTAC for CDK6 Size:2mg solid improving glucose utilization and fattyCP 10 is a PROTAC with highly selective, specific, and remarkable CDK6 degradation (DC50=2. 1 nM). It inhibits proliferation of several haematopoietic cancer cells with impressive potency including multiple myeloma, and can still degrades mutated and overexpressed CDK6 Product information CAS Number: 2366268 80 4 Molecular Weight: 871. 94 Formula: C44H49N13O7 Chemical Name: 4 [(2 {2 [4 ({4 [6 ({6 acetyl 8 cyclopentyl 5 methyl 7 oxo 7H,8H pyrido[2,3