IKarisoside A em monohydrate InChiKey: WUJBXFXHDUVSFM-HWKANZROSA-N

InChiKey: WUJBXFXHDUVSFM-HWKANZROSA-N

Nomanbhoy TK

AZ3451 is a potent antagonist of protease-activated receptor 2 (PAR2) that binds to a remote allosteric site outside the helical bundle with IC50 of 23 nM

2-trifluoro-1-(4'-(methylsulfonyl)-[1

InChiKey: TXJZRSRTYPUYRW-NQIIRXRSSA-N

IKarisoside A em monohydrate InChiKey: WUJBXFXHDUVSFM-HWKANZROSA-NIKarisoside A(Icarisoside A) is a natural compound isolated from Epimedium koreanum (Berberidaceae); has anti inflammatory properties. IC50 value: Target: in vitro: Ikarisoside A inhibited the expression of LPS stimulated inducible nitric oxide synthase (iNOS) and the production of nitric oxide (NO) in LPS stimulated RAW 264. 7 cells and mouse bone marrow derived macrophages (BMMs) in a concentration dependent manner. In addition, Ikarisoside A