BAY-57-1293 - CAS# 348086-71-5 Catalog No.:M6482-10 selective and orally bioavailable HDAC/LSD1
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BAY-57-1293 - CAS# 348086-71-5 Catalog No.:M6482-10 selective and orally bioavailable HDAC/LSD1BAY 57 1293, CAS No. 348086 71 5, is a potent helicase primase inhibitor. BAY 57 1293 inhibits replication of herpes simplex virus (HSV) type 1 and type 2 in the nanomolar range in vitro by abrogating the enzymatic activity of the viral primase helicase complex. In various rodent models of HSV infection the antiviral activity of BAY 57 1293 in vivo was found to be superior compared to all compounds currently used to treat HSV infections. The compound
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