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CL-387785 - CAS# 194423-06-8 60102 CAS Number: 3650-09-7

CL-387785 - CAS# 194423-06-8 60102 CAS Number: 3650-09-7

Name: CL-387785 - CAS# 194423-06-8 60102 CAS Number: 3650-09-7
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CL-387785 - CAS# 194423-06-8 60102 CAS Number: 3650-09-7CL 387785, CAS No. 194423 06 8, also known as EKI 785 , is a n irreversible inhibitor of EGF receptor (EGFR) kinase activity in vivo (IC50 = 250 490 pM). CL 387785 covalently bound to EGF R. It also specifically inhibited kinase activity of the protein (IC50 = 370+ 120 pM), blocked EGF stimulated autophosphorylation of the receptor in cells (ic50 approximately 5 nM), inhibited cell proliferation (IC50 = 31 125 nM) primarily in a cytostatic manner in

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Description

CAS Number: 3650-09-7

CAS Number: 317318-70-0

protein kinase C inhibitor LXS196 binds to and inhibits PKC

Smiles: CC(O)(CN1C=NC=N1)C1=CC=C(C=C1C(F)(F)F)OC1C=CC(Cl)=CC=1

Molecular Weight: 610

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