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Purvalanol A - CAS# 212844-53-6 60256 GSK 2983559

Purvalanol A - CAS# 212844-53-6 60256 GSK 2983559

Name: Purvalanol A - CAS# 212844-53-6 60256 GSK 2983559
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SKU: 3471610302
Price: 20.00 USD
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SKU: 3471610302

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Purvalanol A - CAS# 212844-53-6 60256 GSK 2983559Purvalanol A, CAS No. 212844 53 6, is a potent CDK inhibitor, which effectively suppresses Src mediated transformation by inhibiting both CDKs and c Src. indicating that the activation of CDKs contributes to the c Src transformation. Purvalanol A suppressed the c Src activity as effectively as the Src selective inhibitor PP2, and that it reverted the transformed morphology to a nearly normal shape with less cytotoxicity than PP2. Purvalanol A induced

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Description

GSK 2983559

LOK and human HER2 with IC50 of 4

5-dimethyl-4-(4-hydroxy-3-isopropylbenzyl)phenoxy)methylphosphonicacid

2-hydroxyglutarate (2HG)

pii: S0006-2952(16)30380-X

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