Metarrestin (ML246) Size:100 mg solid InChi: InChI=1S/C17H20N4O5

InChi: InChI=1S/C17H20N4O5

R59022 is able to interrupts thrombin-induced inositol lipid cycling at the level of diacylglycerol and leads to an elevation of protein kinase C activity

TH-302 exhibits potent cytotoxicity to both human and murine MM cells with hypoxic selectivity and dose dependency

Corbett CA

36(9):1348-1357

Metarrestin (ML246) Size:100 mg solid InChi: InChI=1S/C17H20N4O5Metarrestin (ML246) is an orally active and specific perinucleolar compartment (PNC) inhibitor that disrupts the nucleolar structure and inhibits RNA polymerase (Pol) I transcription. Metarrestin blocks metastatic development and extends survival in mouse cancer models. Product information CAS Number: 1443414 10 5 Molecular Weight: 474. 60 Formula: C31H30N4O Chemical Name: Trans 4 (7 benzyl 4 imino 5,6 diphenyl 4,7 dihydro 3H pyrrolo[2,3 d]pyrimidin 3