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Brigatinib-analog - CAS# 1197958-12-5 60061 CS-0087356

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Brigatinib-analog - CAS# 1197958-12-5 60061 CS-0087356Brigatinib analog, CAS No. 1197958 12 5, is an orally active, potent and selective anaplastic lymphoma kinase (ALK) and the epidermal growth factor receptor (EGFR) inhibitor. Brigatinib analog is structurally related to Brigatinib (AP 26113). Brigatinib analog binds to and inhibits ALK kinase and ALK fusion proteins as well as EGFR and mutant forms. This leads to the inhibition of ALK kinase and EGFR kinase, disrupts their signaling pathways and

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Description

CS-0087356

it induced dramatic apoptosis in above AML cells

43(5):645-56

Staurosporine slightly inhibits tumor promotion of Teleocidin

105925-39-1

Brigatinib-analog - CAS# 1197958-12-5 60061 CS-0087356Brigatinib analog, CAS No. 1197958 12 5, is an orally active, potent and selective anaplastic lymphoma kinase (ALK) and the epidermal growth factor receptor (EGFR) inhibitor. Brigatinib analog is structurally related to Brigatinib (AP 26113). Brigatinib analog binds to and inhibits ALK kinase and ALK fusion proteins as well as EGFR and mutant forms. This leads to the inhibition of ALK kinase and EGFR kinase, disrupts their signaling pathways and

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