DO3A tert-Butyl ester ilactone Acalabrutinib demonstrates on-target effects including

Acalabrutinib demonstrates on-target effects including decreased phosphorylation of PLCγ2

thus preventing C-Myc specific DNA binding and target genes regulation

SCHEMBL14685055

000-fold selectivity for PHD2 over other 2OG-dependent dioxygenases

1-dimethylethyl)-9-fluoro-1

DO3A tert-Butyl ester ilactone Acalabrutinib demonstrates on-target effects includingDOTA tert Butyl ester is a benxyl derivative of the cyclic tosamide; can be nitrated directly; is more convenient to incorporate the nitro group after deprotection lithium aluminum hydride. Product information CAS Number: 122555 91 3 Molecular Weight: 514. 70 Formula: C26H50N4O6 Synonym: DO3A tert butyl DO3A t Bu ester Chemical Name: tert butyl 2 {4,7 bis[2 (tert butoxy) 2 oxoethyl] 1,4,7,10 tetraazacyclododecan 1 yl}acetate Smiles: