KY02111 - Wnt Inhibitor. CAS# 1118807-13-8 306 is a potent and selective

is a potent and selective small molecule that enhances hepatocyte functions and promotes the differentiation and maturation of iPSC-derived hepatocytes toward a more mature phenotype in vitro

1884220-36-3

CAS Number: 1030846-42-4

2109424-53-3 (SAG(trans-cis) HCl)

3 nM in a radioactive enzyme assay and is over 100-fold selective for other histone methyltransferases/HMTs

KY02111 - Wnt Inhibitor. CAS# 1118807-13-8 306 is a potent and selectiveKY02111, CAS No. 1118807 13 8, is a potent and selective Wnt signaling pathway inhibitor discovered by a cell based screening, which promotes differentiation of hESCs iPSCs to cardiomyocytes when used at the second stage of differenitation. Sequential use of CHIR99021 (in the first stage to trigger mesoderm induction of hESCs iPSCs) followed by KY02111 (or XAV939, another Wnt signaling inhibitor) produced robust cardiac differentiation of hESCs iPSCs