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ABT-492 Catalog No.:M7915-10 PHA-793887 induced cell-cycle arrest

SKU: 16820036799

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ABT-492 Catalog No.:M7915-10 PHA-793887 induced cell-cycle arrestABT 492 is a non zwitterionic fluoroquinolone antibiotic under development for for the treatment of respiratory and skin infections. Delafloxacin demonstrates excellent antibacterial potency and exhibits a low probability for the selection of resistant mutants in MRSA. Although mutants can be selected at low frequencies in vitro from quinolone resistant isolates, delafloxacin MICs and MPCs remain low and a fitness cost can be observed. Consequently

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Description

PHA-793887 induced cell-cycle arrest

Inhibits GTP binding to CB1-overexpressing cell membranes in vitro (EC50 = 18

4-trihydroxybutan-2-yl)-1

Epub 2019 Mar 31

5R)-3-hydroxy-3-methyl-8-azabicyclo[3

ABT-492 Catalog No.:M7915-10 PHA-793887 induced cell-cycle arrestABT 492 is a non zwitterionic fluoroquinolone antibiotic under development for for the treatment of respiratory and skin infections. Delafloxacin demonstrates excellent antibacterial potency and exhibits a low probability for the selection of resistant mutants in MRSA. Although mutants can be selected at low frequencies in vitro from quinolone resistant isolates, delafloxacin MICs and MPCs remain low and a fitness cost can be observed. Consequently

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