Doramapimod Catalog No.:M10899-10 Brekken RA

Brekken RA

Smiles: CC1SC2=C(C(=N[C@@H](CC(=O)NCCOCCOCCOCC(=O)N[C@H](C(=O)N3C[C@@H](O)C[C@H]3C(=O)NCC3C=CC(=CC=3)C3SC=NC=3C)C(C)(C)C)C3=NN=C(C)N23)C2C=CC(Cl)=CC=2)C=1C

FRAX597 inhibits tumorigenesis of neurofibromatosis type 2 (NF2)-associated Schwannomas

BMS-477118

Smiles: CCC(C)CC(C)CCCCCCCCC(=O)N[C@H]1C[C@@H](O)[C@@H](NCCN)NC(=O)[C@@H]2[C@@H](O)CCN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC1=O)[C@@H](C)O)[C@H](O)[C@@H](O)C1=CC=C(O)C=C1)[C@H](O)CCN

Doramapimod Catalog No.:M10899-10 Brekken RADoramapimod, also known as BIRB 796, is a member of the N pyrazole N' naphthly urea class of p38MAPK inhibitors, which binds to the kinase with both slow association and dissociation rates. BIRB 796 has entered clinical trials for the treatment of autoimmune diseases. Product information CAS Number: 285983 48 4 Molecular Weight: 527. 66 Formula: C31H37N5O3 Chemical Name: 3 [3 tert butyl 1 (4 methylphenyl) 1H pyrazol 5 yl] 1 {4 [2 (morpholin 4