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NPAS2 Polyclonal Antibody, 100ul Thermal Control This locus represents a polymorphic

SKU: 33112518469

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NPAS2 Polyclonal Antibody, 100ul Thermal Control This locus represents a polymorphicNeuronal PAS domain containing protein 2 encoded by NPAS2 is a member of the basic helix loop helix (bHLH) PAS family of transcription factors. A similar mouse protein may play a regulatory role in the acquisition of specific types of memory. It also may function as a part of a molecular clock operative in the mammalian forebrain.

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Description

This locus represents a polymorphic pseudogene| where some individuals contain an allele that can encode a full-length protein| while others have a non-functional allele containing a premature stop codon (reference SNP rs237520) that truncates the coding sequence

This gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes| platelet dense granules| and lysosomes

Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin| but not for the differentiation of pancreatic polypeptide-producing cells

The protein encoded by this gene represents a regulatory subunit of PI3K

The function of this gene has not yet been defined

NPAS2 Polyclonal Antibody, 100ul Thermal Control This locus represents a polymorphicNeuronal PAS domain containing protein 2 encoded by NPAS2 is a member of the basic helix loop helix (bHLH) PAS family of transcription factors. A similar mouse protein may play a regulatory role in the acquisition of specific types of memory. It also may function as a part of a molecular clock operative in the mammalian forebrain.

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