VBY-825 Catalog No.:M8741-10 a first- in-class pan-NADPH oxidase

a first- in-class pan-NADPH oxidase (Nox) inhibitor

Doripenem is the most active carbapenem (MIC90

ClH/c1-19-11-4-2-10(3-5-11)16-13-15-7-6-12(17-13)14-8-9-18

PF-03716556 has a competitive and reversible mode of action

Smiles: C[C@@H]1CC2=C(NC3=CC=CC=C32)[C@@H](C2C(F)=CC(=CC=2F)/C=C/C(O)=O)N1CC(C)(C)F

VBY-825 Catalog No.:M8741-10 a first- in-class pan-NADPH oxidaseVBY 825 is a novel, reversible cathepsin inhibitor with high potency against cathepsins B, L, S and V. Product information CAS Number: 1310340 58 9 Molecular Weight: 535. 55 Formula: C23H29F4N3O5S Chemical Name: (3S) N cyclopropyl 3 [(2R) 3 cyclopropylmethanesulfonyl 2 {[(1S) 2,2,2 trifluoro 1 (4 fluorophenyl)ethyl]amino}propanamido] 2 oxopentanamide Smiles: CC[C@H](NC(=O)[C@H](CS(=O)(=O)CC1CC1)N[C@@H](C1=CC=C(F)C=C1)C(F)(F)F)C(=O)C(=O)NC1CC1