RGFP966(EE) - CAS# 1396841-57-8 3017 The IC50 values against Daudi
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RGFP966(EE) - CAS# 1396841-57-8 3017 The IC50 values against DaudiRGFP966 is a selective HDAC3 inhibitor . S ystemic treatment with RGFP966 facilitates extinction in mice in a manner resistant to reinstatement. A single treatment of RGFP966 enhances extinction of a previously established cocaine conditioned place preference, while simultaneously enhancing long term object location memory within subjects. During extinction consolidation, HDAC3 inhibition promotes a distinct pattern of histone acetylation linked to
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