TAK-242 Catalog No.:M10780-10 Smiles: OCC1=CNC2=CC=CC=C21

Smiles: OCC1=CNC2=CC=CC=C21

PubMed PMID: 24959278

7-methano[1]azacycloundecino[5

InChi: InChI=1S/C26H37N5O5S/c1-4-7-19-18-30(6-3)24-23(19)27-25(28-26(24)33)21-17-20(8-9-22(21)36-16-5-2)37(34

InChi: InChI=1S/C12H14N2

TAK-242 Catalog No.:M10780-10 Smiles: OCC1=CNC2=CC=CC=C21Resatorvid, also known as TAK 242, is a cell permeable inhibitor of TLR4 signaling, blocking LPS induced production of NO, TNF , IL 6, and IL 1 in macrophages with IC50 values of 1 11 nM. Resatorvid binds selectively to TLR4 and interferes with interactions between TLR4 and its adaptor molecules. Resatorvid provides neuroprotection in experimental traumatic brain injury: implication in the treatment of human brain injury. Product information CAS