AZD5363 Catalog No.:M10096-10 is an inhibitor of epidermal

is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 460 µM in the human epidermoid carcinoma cell line A431

CAS Number: 1154097-71-8

Minakuchi K

including suppressing neovascular and angiogenesis

402(2-3):121-3

AZD5363 Catalog No.:M10096-10 is an inhibitor of epidermalAZD5363, also known as Capivasertib, is an orally available inhibitor of the serine threonine protein kinase AKT (protein kinase B) with potential antineoplastic activity. AKT inhibitor AZD5363 binds to and inhibits all AKT isoforms. Inhibition of AKT prevents the phosphorylation of AKT substrates that mediate cellular processes, such as cell division, apoptosis, and glucose and fatty acid metabolism. A wide range of solid and hematological