Savolitinib Catalog No.:M8740-10 It shows selective toxicity to

It shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM)

is a selective Rev-Erbα/β agonist that increases wakefulness

29-triazaspiro[pentacyclo[23

Chemical Name: (2-chloro-10H-phenothiazin-10-yl)(4-methoxyphenyl)methanone

Epub 2012 Nov 3

Savolitinib Catalog No.:M8740-10 It shows selective toxicity toSavolitinib, also known as Volitinib, AZD6094 or HMPL 504, is an orally bioavailable inhibitor of the c Met receptor tyrosine kinase with potential antineoplastic activity. Volitinib selectively binds to and inhibits the activation of c Met in an ATP competitive manner, and disrupts c Met signal transduction pathways. This may result in cell growth inhibition in tumors that overexpress the c Met protein. Product information CAS Number: 1313725 88 0