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Management options may include dose adjustment, temporary treatment interruption, addressing contributing factors (such as optimizing management of gastrointestinal side effects), or considering alternative weight management strategies if symptoms persist and significantly impact quality of life

Instead, DIC mediates electro-neutral exchange of dicarboxylates or GSH for inorganic phosphate ( TISSUE-SPECIFIC FEATURES OF GLUTATHIONE IMPORT TO MITOCHONDRIA Previous studies in a renal proximal tubular cell line, NRK-52E, indicated that overexpression of OGC and DIC increased mGSH levels and protected against oxidant-mediated cell death (Xu et al., 2006)

Glutathione: Metabolism, transport and effects of selective modifications of cellular glutathione levels