Calnexin Polyclonal Antibody, 50ul[BT-AP01127] Metabolic enzymes tool compounds V-ATPase-dependent organelle acidification is necessary

V-ATPase-dependent organelle acidification is necessary for multiple processes including protein sorting

which have been implicated in the regulation of cytoskeletal dynamics

probably through an TIR-TIR domain interaction with TLR4

a member of the FACIT collagen family (fibril-associated collagens with interrupted helices)

This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2

Calnexin Polyclonal Antibody, 50ul[BT-AP01127] Metabolic enzymes tool compounds V-ATPase-dependent organelle acidification is necessaryCANX encodes a member of the calnexin family of molecular chaperones. Calnexin is a calcium binding, endoplasmic reticulum (ER) associated protein that interacts transiently with newly synthesized N linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript