KLHL3 Polyclonal Antibody, 50ul Subcellular Fractions cofactor:Binds 3 calcium ions per

cofactor:Binds 3 calcium ions per subunit

The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP

which is a G-protein coupled receptor

which encode a phylogenetically conserved family of transcription factors that regulate a variety of developmental processes

It associates with the signaling lymphocyte-activation molecule

KLHL3 Polyclonal Antibody, 50ul Subcellular Fractions cofactor:Binds 3 calcium ions perKLHL3 is ubiquitously expressed and encodes kelch like family member 3 which has an N terminal BTB domain followed by a BACK domain and six kelch like repeats in the C terminus. These kelch like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D); a rare