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PKC Alpha Polyclonal Antibody, 100ul[BT-AP07210] Lysosome Plays an important oncogenic role

SKU: 99486859302

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PKC Alpha Polyclonal Antibody, 100ul[BT-AP07210] Lysosome Plays an important oncogenic roleProtein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile

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Description

Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells

Overexpression of this protein has been shown to induce cell death

This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function

Multiple alternatively spliced transcript variants have been found for HIF3A

This gene is located at the junction of certain disease-related chromosomal translocations

PKC Alpha Polyclonal Antibody, 100ul[BT-AP07210] Lysosome Plays an important oncogenic roleProtein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile

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