SH3K1 Polyclonal Antibody, 50ul Pipette Filler The N-terminal FADD-like death effector

The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD

In functional expression studies

and bladder cancer

Two transcript variants resulting from alternative splicing of the 3' terminal exon

leading to the induction of cytokines

SH3K1 Polyclonal Antibody, 50ul Pipette Filler The N-terminal FADD-like death effectorThis gene encodes an adapter protein that contains three N terminal Src homology domains, a proline rich region and a C terminal coiled coil domain. The encoded protein facilitates protein protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin dependent endocytosis. Alternate splicing results in multiple transcript variants.