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FOLR3 Polyclonal Antibody, 50ul Immune Cell Preparation upon B cell activation

SKU: 99158174752

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FOLR3 Polyclonal Antibody, 50ul Immune Cell Preparation upon B cell activationThis gene encodes a member of the folate receptor (FOLR) family of proteins, which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5 methyltetrahydrofolate to the interior of cells. Expression of this gene may be elevated in ovarian and primary peritoneal carcinoma. This gene is present in a gene cluster on chromosome 11. Alternative splicing results in multiple transcript variants.

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Description

upon B cell activation

Members of this family have three conserved domains: an N-terminal homology domain

Ubiquitination of type II deiodinase by the encoded protein is an important regulatory step in thyroid hormone signalling

Alternatively spliced transcript variants encoding different isoforms of this gene have been described

Binds to pre-mRNA in spliceosome C complex

FOLR3 Polyclonal Antibody, 50ul Immune Cell Preparation upon B cell activationThis gene encodes a member of the folate receptor (FOLR) family of proteins, which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5 methyltetrahydrofolate to the interior of cells. Expression of this gene may be elevated in ovarian and primary peritoneal carcinoma. This gene is present in a gene cluster on chromosome 11. Alternative splicing results in multiple transcript variants.

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