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RUVB2 Rabbit Polyclonal Antibody, 20ul Purification A similar but distinct gene

SKU: 99041634240

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RUVB2 Rabbit Polyclonal Antibody, 20ul Purification A similar but distinct geneThis gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB LHB gene cluster on chromosome 19q13. 3 and is very close (55 nt) to the LHB gene in the opposite orientation.

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Description

A similar but distinct gene (TAF9L) has been found on the X chromosome and a pseudogene has been identified on chromosome 19

SRC proto-oncogene

In case of HIV infection| interacts and cleaves the secreted viral Tat protein| leading to a decrease in neuronal Tat's mediated neurotoxicity

The protein localizes to the nucleoplasm and nucleoli

The apoptotic signal is transduced inside these cells by cytoplasmic adaptor proteins

RUVB2 Rabbit Polyclonal Antibody, 20ul Purification A similar but distinct geneThis gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB LHB gene cluster on chromosome 19q13. 3 and is very close (55 nt) to the LHB gene in the opposite orientation.

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