Trk A(Phospho Tyr680/Y681) Polyclonal Antibody, 20ul Shaker&Mixing It consists of two concentric

It consists of two concentric membranes perforated by nuclear pores

Growth/differentiation factor 15 encoded by GDF15 belongs to the transforming growth factor-beta (TGF-beta) family

Mutations in this gene are associated with slow-channel congenital myasthenic syndrome

The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm

Pseudogenes are present on chromosomes 5 and 22

Trk A(Phospho Tyr680/Y681) Polyclonal Antibody, 20ul Shaker&Mixing It consists of two concentricThis gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self mutilating behavior,