TNKS1 Polyclonal Antibody, 20ul Microplate Mixer Binds to insulin-response elements (IREs)

Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1

This gene is most abundantly expressed in testis

Mutations and deficiencies in peroxisomal protein importing and peroxisome assembly lead to peroxisomal biogenesis disorders

and confers oncogenic transformation of primary cells

through calcium-independent cell-adhesion activity

TNKS1 Polyclonal Antibody, 20ul Microplate Mixer Binds to insulin-response elements (IREs)Catalytic activity: NAD(+) + (ADP D ribosyl)(n) acceptor = nicotinamide + (ADP D ribosyl)(n+1) acceptor.,May regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4 GLUT4 vesicles. Has PARP activity and can modify TERF1, and thereby contribute to the regulation of telomere length.,PTM: ADP ribosylated ( auto).,PTM: Phosphorylated on serine residues by MAPK kinases upon insulin stimulation.,Contains 1 PARP catalytic