ABT1 Rabbit Polyclonal Antibody, 20ul Cell Labeling & Imaging Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants have been found| but the full-length nature of some variants has not been defined

It is also highly expressed in FA B-cells of complementation group A

This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway

This protein forms a trimeric complex with cyclin H and MAT2

Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged

ABT1 Rabbit Polyclonal Antibody, 20ul Cell Labeling & Imaging Multiple alternatively spliced transcript variantsBasal transcription of genes by RNA polymerase II requires the interaction of TATA binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activates basal transcription from class II promoters by interaction with TBP and the class II promoter DNA.