PDE1A Polyclonal Antibody, 50ul Micro Centrifuge Tubes It is involved in mammalian

It is involved in mammalian pigmentation

MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain

May be involved in apoptosis signaling in the presence of the reinoid CD437

Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index

The encoded protein localizes to cell membranes and is required for zinc uptake in the intestine

PDE1A Polyclonal Antibody, 50ul Micro Centrifuge Tubes It is involved in mammalianCyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and or cGMP to their respective nucleoside 5 prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+) calmodulin (see CALM1; MIM 114180) dependent PDEs (CaM PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001