JIP4 Polyclonal Antibody, 20ul Fluorescent Staining Gene Ontology (GO) annotations related

Gene Ontology (GO) annotations related to PLK5 include transferase activity

Also found in the colon

The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity| indicating a role as a negative regulator of CDC2/cyclin A

The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors

This gene encodes a member of the granzyme subfamily of proteins

JIP4 Polyclonal Antibody, 20ul Fluorescent Staining Gene Ontology (GO) annotations relatedThis gene encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen activated protein kinases and mediates c Jun terminal kinase signaling. This protein also binds to kinesin 1 and may be involved in microtubule based membrane transport. This protein may play a role in tumor growth and development. Alternate splicing results in multiple transcript variants.