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MCLN2 Rabbit Polyclonal Antibody, 50ul Biomatrix It contains a Sec7 domain

SKU: 96119748835

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MCLN2 Rabbit Polyclonal Antibody, 50ul Biomatrix It contains a Sec7 domainMucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals the mucolipin family includes 3 members MCOLN1 (MIM 605248) MCOLN2 and MCOLN3 (MIM 607400) that exhibit a common 6 membrane spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al. 2007

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Description

It contains a Sec7 domain

Expression of this protein was reduced in human breast cancers while its overexpression reduced tumor growth and metastasis

The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation

This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells

This gene encodes a member of the class-II aminoacyl-tRNA synthetase family

MCLN2 Rabbit Polyclonal Antibody, 50ul Biomatrix It contains a Sec7 domainMucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals the mucolipin family includes 3 members MCOLN1 (MIM 605248) MCOLN2 and MCOLN3 (MIM 607400) that exhibit a common 6 membrane spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al. 2007

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