Mucin 16 Polyclonal Antibody, 50ul Plasma mismatch repair system component encoded

mismatch repair system component encoded by PMS2 is a key component of the mismatch repair system that functions to correct DNA mismatches and small insertions and deletions that can occur during DNA replication and homologous recombination

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Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14

and can activate the nuclear factor-kappaB

Mucin 16 Polyclonal Antibody, 50ul Plasma mismatch repair system component encodedMUC16, also named as CA125, is thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. It is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller subunits being described by some