NPHP3 Rabbit Polyclonal Antibody, 50ul Glassware This complex functions through chromatin

This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells

This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex

ultimately influencing mitogenesis and differentiation

The role it plays in metastasis is unclear

The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains

NPHP3 Rabbit Polyclonal Antibody, 50ul Glassware This complex functions through chromatinThis gene encodes a protein containing a coiled coil (CC) domain a tubulin tyrosine ligase (TTL) domain and a tetratrico peptide repeat (TPR) domain. The encoded protein interacts with nephrocystin it is required for normal ciliary development and it functions in renal tubular development. Mutations in this gene are associated with nephronophthisis type 3 and also with renal hepatic pancreatic dysplasia and Meckel syndrome type 7. Naturally occurring