GPR139 Polyclonal Antibody, 100ul Adeno-associated Virus Packaging 3) associated with gonadal dysgenesis

3) associated with gonadal dysgenesis and XY sex reversal

VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions

This protein is ubiquitously expressed during development and plays a role in many cellular processes associated with cytoskeletal structure

AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors

Among its related pathways are Endocytosis and Notch Signaling Pathways

GPR139 Polyclonal Antibody, 100ul Adeno-associated Virus Packaging 3) associated with gonadal dysgenesisGPR139 encodes a member of the rhodopsin family of G protein coupled receptors. The G protein coupled receptor 139 is almost exclusively expressed in the central nervous system. L tryptophan and L phenylalanine may act as the physiologic ligands of the encoded protein. Alternative splicing results in multiple transcript variants.