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Vinculin Polyclonal Antibody, 50ul[BT-AP09532] Glassware Sets The protein encoded by this

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Vinculin Polyclonal Antibody, 50ul[BT-AP09532] Glassware Sets The protein encoded by thisVinculin is a cytoskeletal protein associated with cell cell and cell matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively

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Description

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule

Alternative splicing of this gene results in two transcript variants encoding different isoforms

This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks

Each isoenzyme is a homodimer composed of 2 alpha

According to PubMed:17823411 highly expressed in testis

Vinculin Polyclonal Antibody, 50ul[BT-AP09532] Glassware Sets The protein encoded by thisVinculin is a cytoskeletal protein associated with cell cell and cell matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively

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