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SIG14 Polyclonal Antibody, 100ul Cell Culture Dishes A subtype of IgA pemphigus|

SKU: 94640149880

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SIG14 Polyclonal Antibody, 100ul Cell Culture Dishes A subtype of IgA pemphigus|Putative adhesion molecule. Sialic acid binding paired receptor which may activate associated receptors.,Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig like lectin) family.,Contains 1 Ig like V type (immunoglobulin like) domain.,Contains 2 Ig like C2 type (immunoglobulin like) domains.,subunit: Interacts with TYROBP.,tissue specificity: Mainly expressed in hematopoietic tissues including bone marrow, spleen and fetal liver.

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Description

A subtype of IgA pemphigus| a life-threatening autoimmune disease| is characterized by the presence of autoantibodies that target the encoded protein

They are known to bind several kinases of intermediary metabolism

It is expressed in adult and embryonic tissues (most notably in placenta) and reported to have a role in cell proliferation

Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene

and it is thought to play a role in the pathogenesis of Alzheimer's disease

SIG14 Polyclonal Antibody, 100ul Cell Culture Dishes A subtype of IgA pemphigus|Putative adhesion molecule. Sialic acid binding paired receptor which may activate associated receptors.,Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig like lectin) family.,Contains 1 Ig like V type (immunoglobulin like) domain.,Contains 2 Ig like C2 type (immunoglobulin like) domains.,subunit: Interacts with TYROBP.,tissue specificity: Mainly expressed in hematopoietic tissues including bone marrow, spleen and fetal liver.

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